3D Printing
News Videos Newsletter Contact us
Home / News / UpNano and BIO INX Collaborate to Bioprint Complex Structures
qidi

UpNano and BIO INX Collaborate to Bioprint Complex Structures

June 21, 2023

Bioprinting technology has taken a significant leap forward thanks to the collaboration between UpNano and BIO INX. The partnership has resulted in the development of a new biocompatible hydrogel resin, Hydrotech INX U200, that enables two-stage 3D printing of organ-on-chip devices with encapsulated live cells.

This novel resin facilitates 2-photon polymerization (2PP) 3D printing at micro- to meso-scale with exceptional resolution, opening the door to fabricating complex and versatile lab-on-chip designs.

UpNano and BIO INX Collaborate to Bioprint Complex Structures
Close-up image of the printed structures. (Image Credit: UpNano)

The joint efforts of BIO INX, a material specialist based in Belgium, and UpNano, an Austrian leader in 2PP 3D printing, have led to the creation of bioinks that combine multiple biocompatible materials. By combining Hydrotech INX U200 with the cell-encapsulating gelatin-based hydrogel Hydrobio INX U200, researchers can now develop highly versatile cancer-on-chip models.

Hydrobio INX U200 is the first commercially available high-resolution bioink that facilitates cell interactivity, further expanding the capabilities of bioprinting.

The advanced features of 2PP 3D printing, such as sub-micrometer resolution combined with the ability to print macro-scale objects, have been amplified by the introduction of Hydrotech INX U200. This bioink, certified for excellent biocompatibility according to ISO 10993-5, enables the precise 2PP 3D printing of macrostructures. It is an ideal choice for organ-on-chip applications due to its bio-inert nature and robust characteristics.

Printing Bioinks with 2PP

To fully utilize the potential of this novel bioink, a state-of-the-art high-resolution 3D printer is necessary. UpNano’s NanoOne 2PP printer range, known for being the fastest high-resolution 3D printing system available, offers an excellent choice. The NanoOne Bio model, specifically designed for printing with living cells under sterile conditions, is a perfect match for fabricating complex 3D scaffolds for cell cultures while embedding living cells into these structures.

The combination of UpNano’s NanoOne Bioprinter and the two bioinks, Hydrotech INX U200 for inert structures and Hydrobio INX U200 for living cells, simplifies the production of complex designs. Hydrotech INX U200 optimizes the high-resolution fabrication of bioinert microstructures, while Hydrobio INX U200 is a water-soluble natural hydrogel that allows for the direct transfer of cell cultures into intricate 3D structures.

This advancement in bioprinting not only offers unprecedented precision but also facilitates the direct embedding of living cells, saving time and enhancing the significance of research results. Lab-on-a-chip devices can now be produced with surface structures resembling natural tissues, allowing the creation of biomimetic structures within microfluidic channels.

Come and let us know your thoughts on our Facebook, Twitter, and LinkedIn pages, and don’t forget to sign up for our weekly additive manufacturing newsletter to get all the latest stories delivered right to your inbox.

Share:
WhatsApp Twitter Facebook LinkedIn Buffer Reddit E-mail
About the author | Phillip Keane
Phillip is an aerospace engineer from UK. He is a graduate of Coventry University (UK), International Space University (France) and Nanyang Technological University (Singapore), where he studied Advanced Manufacturing at the Singapore Centre for 3D Printing.
Join our newsletter

Our newsletter is free & you can unsubscribe any time.

Latest posts

Laser-Assisted Cold Spray Technology Enhances Material Deposition Process

Researchers at the University of Cambridge's Center for Industrial Photonics have developed a new additive manufacturing technique called laser-assisted cold spray (LACS). The... read more »

3D Printing Metal
Laser-Assisted Cold Spray Technology Enhances Material Deposition Process

Titomic Netherlands Secures Strategic Funding to Advance Cold Spray 3D Printing Technology

Titomic Limited, an Australian company specializing in cold spray additive manufacturing, has received €800,000 in funding from the Netherlands' 3D Print Kompas program.... read more »

3D Printing Metal
Titomic Netherlands Secures Strategic Funding to Advance Cold Spray 3D Printing Technology

3D-Printed Insects Help Scientists Map the Limits of Mimicry in Nature

Researchers at the University of Nottingham have developed a method to 3D print life-sized, color-accurate insect models for biological research. The team, led... read more »

Environmental

University of Hong Kong Scientists Explore Growing Organs with 3D Printing Technology

Researchers at the University of Hong Kong (HKU) are working to combine 3D-printed respiratory tissue with lab-grown organoids to create functional airways for... read more »

Bioprinting
University of Hong Kong Scientists Explore Growing Organs with 3D Printing Technology

SHINING 3D Unveils EinScan Rigil with Tri-Mode Scanning for Pro-sumer Flexibility

SHINING 3D has launched its newest flagship 3D scanner, the EinScan Rigil — touted as the world’s first 3D scanner featuring Tri-Mode operation... read more »

News
SHINING 3D Unveils EinScan Rigil with Tri-Mode Scanning for Pro-Level Flexibility

ETH Zurich 3D Prints Recycled Plastic Structure for Swiss Ice Cream Shop

ETH Zurich students have completed a 3D-printed ice cream shop in the Swiss Alpine village of Mulegns. The project, called Gelateria, was designed... read more »

Construction
ETH Zurich 3D Prints Recycled Plastic Structure for Swiss Ice Cream Shop

Hugo Launches 3D Printed Loafers with Zellerfeld

Hugo, the younger brand under Hugo Boss, has partnered with 3D printing company Zellerfeld to create a fully 3D-printed loafer. The shoe is... read more »

Fashion
Hugo Launches 3D Printed Loafers with Zellerfeld

3D Printed Resin Combines Rubber Flexibility with Plastic Strength, Surprising Scientists

Researchers at the University of Texas at Austin have developed a 3D printing method that can create objects with both soft and hard... read more »

News
3D Printed Resin Combines Rubber Flexibility with Plastic Strength, Surprising Scientists

LPE Supports Queen’s Propulsion Laboratory with 3D Printed Rocket Engine Chamber

Students at Queen's University Belfast have developed what they describe as Ireland's first student-built liquid rocket engine. The Kelvin Mk.1, named after Belfast-born... read more »

3D Printing Metal
LPE Supports Queen’s Propulsion Laboratory with 3D Printed Rocket Engine Chamber

Social

  • Facebook Facebook 3D Printing
  • Linkedin Linkedin 3D Printing
Join our newsletter

Our newsletter is free & you can unsubscribe any time.

Featured Industries

  • Automotive
  • Aerospace
  • Construction
  • Dental
  • Environmental
  • Electronics
  • Fashion
  • Medical
  • Military
  • QIDI Plus4

    • - Print size: 305 x 305 x 280 mm
    • - print temperature of 370°C
    More details »
    $799.00 QIDI Store
    Buy Now
  • QIDI Tech Q1 Pro

    • - Print size: 245 x 245 x 245 mm
    • - 600mm/s max speed
    More details »
    $449.00 QIDI Store
    Buy Now
  • QIDI Tech X-Max 3

    • - Print size: 325 x 325 x 315 mm
    • - fully enclosed
    More details »
    $799.00 QIDI Store
    Buy Now
  • Snapmaker Artisan Premium 3-in-1

    • - Print size: 400 x 400 x 400 mm
    • - comes with enclosure
    More details »
    $2,999.00 Snapmaker
    Buy Now

Company Information

  • What is 3D Printing?
  • Contact us
  • Join our mailing list
  • Advertise with us
  • Media Kit
  • Nederland 3D Printing

Blog

  • Latest News
  • Use Cases
  • Reviews
  • 3D Printers
  • 3D Printing Metal

Featured Reviews

  • Anycubic Photon Mono M5s
  • Creality Ender 5 S1
  • The Mole 3D Scanner
  • Flashforge Creator 3 Pro

Featured Industries

  • Automotive
  • Aerospace
  • Construction
  • Dental
  • Environmental
  • Electronics
  • Medical
  • Military
  • Fashion
  • Art
2025 — Strikwerda en Dehue
  • Home
  • Join our mailing list
  • Contact us
Blog
  • Latest News
  • Use Cases
  • Reviews
  • 3D Printers
  • 3D Printing Metal
Featured Industries
  • Automotive
  • Aerospace
  • Construction
  • Dental
  • Environmental
  • Electronics
  • Medical
  • Military
  • Fashion
  • Art
Company Information
  • What is 3D Printing?
  • Contact us
  • Join our mailing list
  • Advertise with us
  • Media Kit
  • Nederland 3D Printing