Georgia Tech researchers have developed a new type of 3D-printed heart valve designed to promote natural tissue regeneration. The bioresorbable valve aims to address limitations of current replacement options, which typically last only 10-15 years. This innovation could particularly benefit the millions of Americans affected by heart valve disease, who often require multiple surgeries throughout their lives.
The new valve is manufactured using poly(glycerol dodecanedioate), a biocompatible material that can be inserted via catheter. Once in place, the valve responds to body temperature by taking its intended shape and encouraging tissue growth. The original printed structure dissolves within months, leaving behind naturally regenerated valve tissue.
The technology offers particular promise for pediatric patients, who currently face repeated surgeries as they grow. “In pediatrics, one of the biggest challenges is that kids grow, and their heart valves change size over time,” said Scott Hollister, who holds the Patsy and Alan Dorris Chair in Pediatric Technology at Georgia Tech.
The project combines two existing technologies – bioresorbable implants and 3D-printed valves – in a novel way. The research team, led by faculty members Lakshmi Prasad Dasi and Scott Hollister, focused on creating patient-specific solutions rather than following the traditional one-size-fits-most approach.
While the innovation shows potential, significant testing remains before the valve can enter clinical use. The research team is currently conducting durability tests and simulations that mirror real heart conditions. The project has received funding from the National Institutes of Health and involves multiple researchers working on various aspects of the technology’s development.
Source: research.gatech.edu